The Hatsopoulous and Ross Labs at the University of Chicago, pioneered the simultaneous recording of 3D jaw and tongue kinematics using XROMM and activity in populations of neurons in the orofacial sensorimotor cortex using multi-electrode arrays. These data are providing new insights into cortical control of orofacial function, including bite force, gape, and jaw and tongue movements. We are currently comparing grasping and biting behaviors to determine whether the same cortical control mechanisms are used in the two systems.

Related Publications

Biomechanical and Cortical Control of Tongue Movements During Chewing and Swallowing
Callum F Ross, JD Laurence-Chasen, Peishu LI, Courtney Orsbon, Nicho Hatsopoulos. Dysphagia. (2023) [PDF] [DOI]

Directional information from neuronal ensembles in the primate orofacial sensorimotor cortex
Arce, FI, Lee, J-C, Ross, CF, Sessle, BJ, Hatsopoulos, N. Journal of Neurophysiology. 110: 1357-1369 (2013)

Dynamics of motor cortical activity during naturalistic feeding behavior 
Liu, S, Iriarte-Diaz, J, Hatsopoulos, NG, Ross, CF, Takahashi, K, Chen, Z. Journal of Neural Engineering.. 16(2): 026038 (2019) [DOI]

Gape drives regional variation in temporalis architectural dynamics in tufted capuchins
Myra F. Laird, Jose Iriarte-Diaz, Craig D. Byron, Michael C. Granatosky, Andrea B. Taylor and Callum F. Ross. Philosophical Transactions of the Royal Society B. 378: 20220550. (2023) [PDF] [DOI]

Granger causality analysis of state dependent functional connectivity of neurons in orofacial motor cortex during chewing and swallowing 
Takahashi, K, Pesce L, Best M, Iriarte-Diaz J, Kim S, Coleman TP, Hatsopoulos NG, and Ross, CF. Proceedings of 6th International Conference on Soft Computing and Intelligent Systems, Kobe, Hyogo, Japan. Nov., 2012: 1067-1071 (2012)

Loss of tactile feedback impairs feeding performance and consistency of tongue-jaw coordination
Laurence-Chasen, JD, Arce-McShane, FI, Hatsopoulos, NG, Ross, CF. Journal of Oral Rehabilitation. (2022) [DOI]

Modulation dynamics in the orofacial sensorimotor cortex during motor skill acquisition
Arce, FI, Hatsopoulos, NG, Lee, J-C, Ross, CF, Sessle, BJ. Journal of Neuroscience. 34(17): 5985-97 (2014)

Multiple regions of sensorimotor cortex encode bite force and gape
Arce-McShane, F; Sessle, BJ, Ram Y; Ross CF; Hatsopoulos NG. Frontiers in Systems Neuroscience. (2023) [PDF] [DOI]

Primary motor and sensory cortical areas communicate via spatiotemporally coordinated networks at multiple frequencies
Arce-McShane, FI, Takahashi, K, Ross, CF, Sessle, BJ, Hatsopoulos, NG. Proceedings of National Academy of Sciences. 113 (18): 5083-5088 (2016) [DOI]

Primary sensorimotor cortex exhibits complex dependencies of spike-field coherence on neuronal firing rates, field power, and behavior
Arce-McShane, FI, Sessle, BJ, Ross, CF, Hatsopoulos, NG. Journal of Neurophysiology. 2018 Jul 1;120(1):226-238 (2018) [DOI]

Recurrence network analysis of multiple local field potential bands from the orofacial portion of primary motor cortex
Subramaniyam, NP, Hyttinen, J, Hatsopoulos, NG, Ross, CF, Takahashi, K. Conference Proceedings of the IEEE, Engineering in Medicine and Biology Society. 2015: 5343-5346 (2015) [DOI]

Robust cortical encoding of 3D tongue shape during feeding in macaques
JD Laurence-Chasen, Callum F Ross, Fritzie Arce-McShane, Nicho Hatsopoulos. Nature Communications. Nature Communications | ( 2023) 14:2991 (2023) [PDF] [DOI]